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Organovo: 3d Printing Living Tissue

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Organovo: 3d Printing Living Tissue

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Organovo is a medical research company headquartered in San Diego which designs and develops three dimensional human tissue. The living 3D printed tissue can be used for testing drugs before giving the drugs to a real person.  Organovo uses a proprietary bioprinting platform called NovoGen for 3D printing tissue.

Pharmaceutical companies conventionally perform testing on animals or on cells in petri-dishes.  Both methods of testing are very different from testing on a living person.  Therefore several clinical trials fail when tried on living person even if they were considered successful on animals or cells in petri-dish.  Organovo technology bridges this gap by providing 3D tissue models that are much closer to a living person.  Pharmaceutical companies can use the 3D tissues developed using this technology for testing.

In 2014 Organovo announced commercial release of exVive3DTM Human Liver Tissue for preclinical drug discovery testing.  In April 2015, Organovo presented results of 3D printing in vitro 3D kidney tissue at the 2015 Experimental Biology conference in Boston.  In 2015 L’Oreal signed an agreement with Organovo to produce 3D printed skin for use in testing of cosmetics.  The long term goal of Organovo’s 3D bioprinting technology is to be able to create organs for transplantation.

http://www.organovo.com

https://en.wikipedia.org/wiki/Organovo

Orgonovo Company Profile Video

Youtube video of interview with Keith Murphy, CEO of Organovo

Youtube Video: 3D Bioprinter

 

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Strata 3D University

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Strata 3D University

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Strata 3D University is an online resource offering tutorials and learning resources for Strata software products.  The primary Strata product covered is Design 3D. Design 3D is a professional level 3D modeling and animation software offered by Strata. Strata 3D University offers more than a thousand tutorial videos.  They offer a month-to-month subscription or a 12 month subscription.

Design 3D is a software offered by Strata that allows modeling of 3D objects that can be 3D printed. Design 3D allows exporting designs created to file formats that are accepted by many 3D printers. Since Design 3D is a very versatile tool for 3D modeling, not all designs created using Design 3D may be suitable for 3D printing.  Designers have to follow certain guidelines to create designs that can be 3D printed.

https://www.strata.com/university/

strata.com/design-3d-cx-8-for-mac/

strata.com/design-3d-cx-for-windows/

support.strata.com/index.php?action=artikel&cat=7&id=456&artlang=en

Blooms: Strobe Animated 3D Printed Sculptures

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Blooms: Strobe Animated 3D Printed Sculptures

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John Edmark, an inventor and designer who teaches at Stanford University has designed 3D printed sculptures called blooms that animate when spun and lit by a strobe light. These sculptures can be used to create fascinating animations using a video camera with a fast shutter speed.  The 3D printed sculpture is rotated at a particular speed synchronized with the shutter speed of the video camera that captures a picture every time the object turns by a particular angle.  As a result, fascinating animations are created as shown in the videos below.  These designs are available for printing from shapeways (http://www.shapeways.com/shops/edmark.)  A turntable and a strobe light is needed to animate a bloom.  Generating an animation using a bloom is similar to zoetrope (https://en.wikipedia.org/wiki/Zoetrope.)  The number of spirals on each sculpture are always Fibonacci numbers.  Therefore these are also called Fibonacci Zoetropes.

EDMARK2

http://web.stanford.edu/~edmark/

http://web.stanford.edu/~edmark/FLV/video.htm

http://www.instructables.com/id/Blooming-Zoetrope-Sculptures/

 

 

 

Microfactories: The Next Industrial Revolution based on 3D Printing

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Microfactories: The Next Industrial Revolution based on 3D Printing

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Over half a century, computers have reduced in size from machines that were as big as a house to machines that can be carried in a pocket.  Besides as the computers have become smaller they have become more and more powerful. A computer in a phone that can be carried in a pocket is orders of magnitude more powerful than the computers of the past that were as big as a house.

There is a similar trend in manufacturing thanks to 3D printing.  Car factories need a large amount of space, huge machinery, and a large number of workers to make cars.  This is so because different machinery is needed for making each part of car.  However, companies such as local motors have started the trend of microfactories.  Together, these machineries need a huge amount of space and a large number of workers.  Now, a 3D printer can make most of the parts of a car.  Some of the complex parts are imported.   But the overall manufacturing of the car can be performed in a small location with only few workers.  Such manufacturing facilities are called microfactories.  These microfactories can be established closer to cities and create local jobs.  They reduce distribution costs and are therefore environmentally friendly.  Also cars can be manufactured to suit local needs.  Local motors has already opened microfactories in Phoenix, Las Vegas, and Crystal City, VA.  Local motors aims at opening 100 microfactories in next 10 years.

Another car manufacturer Divergent Microfactories is establishing microfactories to make 3D printed cars.

Strati: a 3D printed car from local motors.

strati

Kevin Czinger, CEO of Divergent Microfactories showing a prototype 3D printed car.

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https://localmotors.com/3d-printed-car/

http://www.divergentmicrofactories.com/