Columbia University Vagelos College of Physicians and Surgeons
Growing human hair in a dish using 3D printing.
According to Angela Christiano, Ph.D., the Richard & Mildred Rhodebeck Professor of Dermatology at Columbia University Vagelos College of Physicians and Surgeons, “Our previous studies implicated JAK-STAT signaling as one potential new therapeutic pathway for hair loss disorders by targeting hair follicle stem cells with JAK inhibitors. A biotech company recently reported results of a small phase 2 trial of a topical JAK-STAT inhibitor based on these studies. Here, we show that blocking the source of the JAK activating signal outside the hair follicle is another way to target this mechanism.”
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