bioprinting

Mushtari: A 3D Printed Wearable Skin from MIT Mediated Matter in collaboration with Stratasys

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Mushtari: A 3D Printed Wearable Skin from MIT Mediated Matter in collaboration with Stratasys

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Professor Neri Oxman of MIT Media Lab revealed a 3D printed wearable at TED2015 in May 2015 in Vancouver.  The wearable is designed to host living matter and was called Mushtari, meaning giant.  Mushtari was 3D printed using a color multi-material 3D Printer developed by Stratasys. This is the world’s first wearable that combines multi-material additive manufacturing and synthetic biology.

photosynthesis to convert sunlight to sugar.  The compatible microbes consume the sugar to

Mushtari is based on synthetic biology.  It uses a symbiotic relationship between a photosynthetic microbe and compatible microbes.  The photosynthetic microbes use generate substances useful for the wearer such as pigments, food, fuel and scents. In future, the wearer could trigger the production of these substances.

 

According to Neri Oxman, “This is the first time that 3D printing technology has been used to produce a photosynthetic wearable piece with hollow internal channels designed to house microorganisms. Inspired by the human gastrointestinal tract, Mushtari hosts synthetic microorganisms, a co-culture of photosynthetic cyanobacteria and E. coli bacteria that can fluoresce bright colors in darkness and produce sugar or biofuels when exposed to the sun. Such functions will in the near future augment the wearer by scanning our skins, repairing damaged tissue and sustaining our bodies, an experiment that has never been attempted before.”

 

 

 

http://matter.media.mit.edu/environments/details/wanderers-living-mushtari

 

http://www.materialecology.com/projects/details/mushtari

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Organovo: 3d Printing Living Tissue

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Organovo: 3d Printing Living Tissue

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Organovo is a medical research company headquartered in San Diego which designs and develops three dimensional human tissue. The living 3D printed tissue can be used for testing drugs before giving the drugs to a real person.  Organovo uses a proprietary bioprinting platform called NovoGen for 3D printing tissue.

Pharmaceutical companies conventionally perform testing on animals or on cells in petri-dishes.  Both methods of testing are very different from testing on a living person.  Therefore several clinical trials fail when tried on living person even if they were considered successful on animals or cells in petri-dish.  Organovo technology bridges this gap by providing 3D tissue models that are much closer to a living person.  Pharmaceutical companies can use the 3D tissues developed using this technology for testing.

In 2014 Organovo announced commercial release of exVive3DTM Human Liver Tissue for preclinical drug discovery testing.  In April 2015, Organovo presented results of 3D printing in vitro 3D kidney tissue at the 2015 Experimental Biology conference in Boston.  In 2015 L’Oreal signed an agreement with Organovo to produce 3D printed skin for use in testing of cosmetics.  The long term goal of Organovo’s 3D bioprinting technology is to be able to create organs for transplantation.

http://www.organovo.com

https://en.wikipedia.org/wiki/Organovo

Orgonovo Company Profile Video

Youtube video of interview with Keith Murphy, CEO of Organovo

Youtube Video: 3D Bioprinter