3D Print Biotechnology and 4D printed Biotechnology Neuroscience.
3D Printer for living tissue
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Danny Cabrera, the co-founder of Biobots, says, “As soon as you get a BioBot, you can print something. What we’re doing is we’re saying anybody can do this. [It’s] this MakerBot of biology idea.”
Biobots says,” a Philadelphia-based startup has developed a desktop 3D printer for printing biomaterials. The 3D printer called BioBot 1 was demoed at TechCrunch Disrupt NY in May 2015. Biobots was found the most innovative startup out of 48 startups at the SXSW Accelerator in Austin.
Biobot 1 uses a compressed air pneumatic system that allows it to precisely control the printing operation. Biobots have developed biomaterial that is placed in the syringe along with cells for printing. The biomaterial hardens as it is extruded. Biobot 1 uses visible blue light to cure the biomaterial. Unlike UV light, visible blue light is not harmful to living tissue. The technology can be used to 3D print living tissue such as cartilage, bone, or liver. The technology can find valuable applications in the clinical development of the drug.
Biobots aims at bringing down the cost of bioprinting significantly. Typical bioprinters cost in the range of hundred thousand dollars. Biobots managed to bring down the cost by an order of magnitude. Biobot 1 is also designed for ease of use.¨
The world’s only six-axis 3D bioprinter.
Meet BioBot, the ‘MakerBot of biology.’
BioBots Is A 3D Printer For Living Cells.
Bioprinter startup BioBots wins ‘Most Innovative’ at SXSW Accelerator.
3D printed human tissues using DNA
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As mentioned by Professor Gartner of UCSF, ¨have developed a technique to build tiny models of human tissue called organoids. The technique uses DNA to guide the assembly of cells into organoids. This technique is called DNA Programmed Assembly of Cells (DPAC). The research team created several organoid arrays mimicking human tissues such as mammary glands. The research was published in the journal Nature Methods on Aug. 31, 2015.
This technique incubates cells with snippets of single strands of DNA The DNA attaches to the cell’s outer membrane. The incubated cell attaches to other cells that are incubated with matching DNA strands. In other words, the cell doesn’t attach with other incubated cells if their DNA sequence does not match. A cell can be incubated with more than one type of DNA cell. This allows the cell to attach to different types of cells. This technique is similar to playing with Legos. A lego piece can attach to other lego pieces if they have matching sides. This simple trick allows lego pieces to be combined to build a very large variety of toys. Similarly, DPAC uses DNA strands attached to cells to create different types of organoids.¨
Building Human Breast Tissue, Cell by Cell.
DNA-guided 3-D printing of human tissue.
3D Tissue Printing Using a DNA Guidance System.
Researchers Discover Way to Print Out Human Tissue.
Programmed synthesis of three-dimensional tissues.
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